Morphological variation of Dalen-Fuchs nodules in sympathetic ophthalmia.

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Morphological variation of Dalén-Fuchs nodules in sympathetic ophthalmia.

Fifty cases of sympathetic ophthalmia were examined histologically to determine the incidence and morphology of Dalén-Fuchs nodules. At least one well-defined Dalén-Fuchs nodule was identified in 18 (36%) of the eyes examined. Three types of lesions at the level of the retinal pigment epithelium were recognised. One type was found to consist of focal hyperplasia and aggregation of retinal pigme...

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Sympathetic ophthalmia (SO) is a rare bilateral, diffuse granulomatous panuveitis that occurs following penetrating trauma or intraocular surgery to one eye, the exciting eye. The fellow non-traumatized sympathizing eye also shows similar inflammatory response usually with mutton-fat KPs suggesting involvement of autoimmune response [1]. Though the time from ocular injury to onset of SO was sai...

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Sympathetic ophthalmia: to the twenty-first century and beyond

Sympathetic ophthalmia is a rare bilateral granulomatous inflammation that follows accidental or surgical insult to the uvea of one eye. Onset of sympathetic ophthalmia can be insidious or acute, with recurrent periods of exacerbation. Clinical presentation shows mutton-fat keratic precipitates, choroidal infiltrations, and Dalen-Fuchs nodules. Histopathology reveals diffuse or nodular granulom...

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Sympathetic ophthalmia presenting with signs of frosted branch angiitis: Report of a case

Sympathetic ophthalmia is an ocular inflammatory disease commonly associated with penetrating trauma. We report a case of sympathetic ophthalmia who had Dalen-Fuchs nodules on presentation and developed a frosted branch angiitis (FBA)-like picture which is not a known feature of this disease. A 25-year-old male patient was seen 8 months following penetrating trauma to the left eye. He was treat...

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We reviewed the charts of 20 patients with sympathetic ophthalmia who were seen in the uveitis clinic at the Eye and Ear Infirmary within an 11-year period. Of these 20 patients 14 maintained 20/50 or better visual acuity in at least one eye. We found early enucleation to be associated with a better visual prognosis, possibly due to earlier diagnosis and faster, more aggressive therapy rather t...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1985

ISSN: 0007-1161

DOI: 10.1136/bjo.69.3.197